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HLA-DR Haplotype Definitions



17-2-52C 



17-2-52C - Benign
 
With regard to biotoxin susceptibility this haplotype is reported to confer no additional risk1. This is a good haplotype to have. It is not specifically correlated with increased susceptibility to mold, lyme or other biotoxins. That is not to say it is not possible to become sick, rather, this haplotype is not one of those that is statistically correlated with or is known to confer additional risk or susceptibility to any of the above mentioned biotoxins.
 

Disease Risk
    û Some versions of this haplotype may confer additional risk of Type 1 Diabetes2
    û Some versions of this haplotype may confer additional risk of Systemic Lupus Erythematosus3
    û This haplotype may confer additional risk of Celiac Disease4
    û This haplotype may confer additional risk of Sjorgen's Syndrome5
    û This haplotype may confer additional risk of Addison's Disease6
    û Elements of this haplotype may confer additional risk of Multiple Sclerosis7
    û Some versions of this haplotype may confer additional risk of Grave's Disease8
 

Disease Protection
    ✓ Elements of this haplotype are reported to be protective agasint Alopecia areata9



References
1.  Surviving Mold, by Ritchie C. Shoemaker
2.  http://diabetes.diabetesjournals.org/content/57/4/1084
3.  http://www.nature.com/ejhg/journal/v15/n8/full/5201827a.html
4.  https://www.ncbi.nlm.nih.gov/pubmed/24628273
5.  https://www.ncbi.nlm.nih.gov/pubmed/11469461
6.  https://www.ncbi.nlm.nih.gov/m/pubmed/11836294
7.  https://www.ncbi.nlm.nih.gov/pubmed/21440682
8.  https://www.ncbi.nlm.nih.gov/pubmed/10468973
9.  https://www.ncbi.nlm.nih.gov/pubmed/16935791