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HLA-DR Haplotype Definitions

4-4-53

4-4-53 - Benign

With regard to biotoxin susceptibility this haplotype is reported to confer no additional risk1. This is a good haplotype to have. It is not specifically correlated with increased susceptibility to mold, lyme or other biotoxins. That is not to say it is not possible to become sick, rather, this haplotype is not one of those that is statistically correlated with or is known to confer additional risk or susceptibility to any of the above mentioned biotoxins.

Disease Risk

û Some versions of elements of this haplotype may confer additional risk of Rheumatoid Arthritis2 û Elements of this haplotype may confer additional risk of Alopecia areata3

References

1.   Surviving Mold, by Ritchie C. Shoemaker 2.   https://www.ncbi.nlm.nih.gov/pmc/articles/pmc130004 3.   https://www.ncbi.nlm.nih.gov/pubmed/16935791